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For translation of the preclinical PK model to humans, allometric scaling was applied and the "humanized" PK model successfully predicted existing plasma PK of remoxipride as measured in humans (67).
In 1978, working with his graduate student, Lyn Abramson, and John Teasdale, a psychologist at Oxford specializing in depression, Seligman began to apply the model to humans.
These studies explored the closest feasible model to humans and provided an opportunity to compare the effects of BoNT-A and BoNT-B injected at doses producing equivalent paresis in contralateral muscles of the same preparation.
"It's very hard to translate" the disease progression in this monkey model to humans, Kobinger said.
Since there are no data corresponding to various other gait parameters, additional gait examinations to connect the rodent model to humans with pain are needed.
But researchers can test how the live virus attacks different cells in culture and can observe the disease's progression in nonhuman primates a nearly identical model to humans.
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Deep learning is recently regarded as the closest artificial intelligence model to human brain.
Appeal the urban governance to change its way from developmental model to human model and rewrite our life into Taipei.
We compare our model to human learners on a challenging task of estimating multiple physical parameters in novel microworlds given short movies.
Our data caution extrapolation of findings about F. tularensis within the murine model to human infection.
To link the model to human performance, we ran 25-trial simulations for each cube.
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