Sentence examples for model to explain the toxicity of from inspiring English sources

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In summary, our working model to explain the toxicity of Aβ in Alzheimer's disease proposes the existence of diverse membrane structures that can progress from a small, ion selective pore, to a large membrane perforation (Fig. 6).

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Many hypotheses including aggregation and oxidative damage have been proposed to explain the toxicity of SOD1 [9], [9].

Another possible mechanism to explain the toxicity of amyloid deposits is direct toxicity to cells [ 2].

This mechanism has been proposed to explain the toxicity of amyloid peptides (reviewed by [ 49– 53]).

However, the toxicity observed by ionic cobalt alone did not explain the toxicity of the WC-Co nanoparticles, suggesting that the combination of metallic Co and WC is the cause of the increased particle toxicity of WC-Co.

This could explain the toxicity of C. speciosus teas reported in ethnobotanical accounts [ 4].

An important question is whether we can explain the toxicity of ginkgolides in insects, and the lack of toxicity in humans.

Our results provide a new model that explains the toxicity of expanded polyQ proteins, in which the interplay between polyQ regions and other aggregation-prone domains plays a key role in determining the aggregation pathway.

This may partly help to explain the cell toxicity of heavy metals in mammalian cells.

Although coating-dependent toxicity was noticeable between two types of Ag NPs evaluated, particle size and surface charge were not adequate to explain the observed toxicity; hence, the toxicity appeared to be material-specific.

Detailed biodistribution profiles could give more useful information to explain the mechanism of toxicity [21 23].

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