Sentence examples for model to explain the promiscuity of from inspiring English sources

The global motion of the domains was studied using a Gaussian Network Model to explain the promiscuity of the PDZ domain [7].

The structures explain the promiscuity of the proteins for peptide binding.

Several mechanisms have been invoked to explain the gain of novel gene function for duplicated genes such as dosage compensation, epigenetic complementation, moonlighting, and catalytic promiscuity [ 12- 17].

To explain the appearance of many closely related families which group into mechanistically diverse superfamilies, Glasner et al. [ 7] have proposed to distinguish two degrees of promiscuity: shared chemistry (substrate ambiguity) and substrate binding (catalytic promiscuity).

In summary, our measure of domain versatility indicates that a random attachment process is sufficient to explain the observed distribution of domain arrangements and that several views on domain promiscuity need to be revised.

This can be probably explained by the promiscuity of siramesine.

Here, a modular metabolic engineering system was used to examine the promiscuity of DTSs.

In this work, we analyzed a dataset comprising 157 compounds, which have been tested at concentrations of 1 μM and 10 μM against a panel of 225 human protein kinases in full-matrix experiments, aiming to explain kinase promiscuity and selectivity against inhibitors.

According to the previously proposed random model of evolution [ 29], the promiscuity of a domain defined in terms of co-occurrences is tightly linked to the frequency of a domain.

This mechanism can also explain the observed catalytic promiscuity of OMPD.

A comparable mechanism might very well explain the metal ion promiscuity of QDO.