Because the vector modeling the transient activation of the presentation of the instruction and the vector modeling the sustained activation are correlated, we cannot completely rule out the possibility that there is sustained activation in the paracingulate area.
While the latter had to be invoked in order to make the model match the sustained deposition fluxes, it is well established that methylotrophic bacteria inhabit plant surfaces and soils (Conrad, 1996; Fall and Benson, 1996; Conrad and Claus, 2005; Kolb, 2009; Stacheter et al., 2013) and may significantly reduce net leaf and ecosystem methanol emissions (Abanda-Nkpwatt et al., 2006).
Our results show, for the first time in a non-transformed IEC model, that the sustained activation of signals downstream of either Grb2 or Shc alone is sufficient to promote morphological transformation, E-cadherin down-regulation, enhanced cell growth, loss of contact inhibition of growth, the acquisition of anchorage-independence of growth, and anoikis resistance.
In a review on Gray's paradox, Fish3 questioned the estimation of power that uses a muscle model based on the sustained performance of oarsmen.
In our model, we explain the sustained [Ca2+]i increase during stimulation with 500 μM TLC-S by depolarization of mitochondria.
However, studies by [ 9, 43], which we have used to inform our model, showed that the sustained ERK signal from NGF stimulation is a result of Rap1/B-Raf activity, and that Ras/Raf-1 is only used transiently under NGF.
First, complying with recent cognitive behavioral and self-regulation models [ 71, 72], the sustained arousal model allows heterogeneity of causal factors among individuals.
Likewise, for the full model, the lowlands sustained higher speciation rates than the highlands.
Furthermore, the sustained arousal model shares several basic aspects with recently proposed models for the overtraining phenomenon in sports medicine [ 75], the posttraumatic stress disorder [ 76], and subjective health complaints [ 30] The CFS sustained arousal model holds the capacity to explain all main findings concerning CFS disease mechanisms within a unifying theoretical framework.
