Sentence examples for model the splicing from inspiring English sources

Therefore, there is a dilemma on using either of the two methods to exactly model the splicing pattern of a specific exon, but this is beyond the scope of our study.

While confirming many earlier predictions, our study also provides a number of new observations that are largely consistent with existing models of the splicing mechanisms.

The observed base-pairing interactions are not necessarily inconsistent with established models of the splicing process, according to which spliceosomal snRNAs interact with the donor site and the branchpoint sequence, since the base-pairing can be easily disrupted after the splicing factors have been aligned properly.

Our results are consistent with a model in which the splicing machinery recognizes intronic sequences.

The humanized IVSI-110 mouse model accurately mimics the splicing defect found in β-thalassemia patients with this mutation.

Artemis can be used to correct gene models if the splice site is wrong, as is the case for this gene.

Although the high proportion of retained introns in AS events in plants supports the intron definition model in splicing, the evidence that the size of the retained introns was more similar to typical exons, lack of long introns, makes the exon definition model an alternative reasonable explanation.

Based on the above assumptions, Ng et al. [10] modeled the image splicing as perturbation of the authentic counterpart with a bipolar signal.