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In the standard DNA slippage model, the slippage probability should be multiplied by the number of sites where slippage can occur (i.e., STR length) leading to a linear relationship between mutation rate and STR length.
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Both studies use only the reference genome(s) and mathematical models to estimate the slippage threshold.
During straight motion, the slippage model was based on the interaction between the track and terrain, and was linear to the roll and pitch angles of the robot.
The finding of repeat sequences in the 3' tail of the HAmo SINEs strengthened the slippage model for initiation of reverse transcription.
In the "transcriptional slippage" model, the presence of an SHS element at the junction seems essential; whereas in the "trans-splicing" model, the appearance of novel exons found in many of the CGs cannot be explained.
In the tandem slippage model, the P-site anticodon re-pairs from XXY to XXX, whereas the A-site anticodon re-pairs from YYZ to YYY, allowing for perfect re-pairing except at the wobble position [ 13].
In the model, contact and slippage between the components were accommodated.
This distribution is consistent with the previously proposed ramp-threshold model for slippage kinetics [5]: at the time of mitotic entry, level of cyclin B1 starts to decrease (i.e. ramp down) with approximately linear kinetics, until it drops below a threshold that is required to sustain mitotic arrest [7], [9].
This model of slippage depends on the presence of repetitive DNA stretches such that the nascent strand could anneal to both locations.
In this study, Lucas-Washburn (LW) theory is revisited by further considering the effective viscosity and slippage to accurately model the capillary filling behaviors in nanopores, where the effective viscosity is investigated by considering the energy barrier induced by pore wall while the true slip is modelled with the wettability by considering the mobility of first-liquid-layer molecules.
An analytical model and finite element (FE) model considering slippage effect are established to obtain the cured shape and deformation of cross-ply [Al/0/90/Al] FMLs.
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