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Given the method's applicability to both hydrophobic and hydrophilic cargo, it could be employed to model the release of any drug-carrier combination.
The culminating argument of each program is a 'Safety Case' for a specific disposal concept containing, among other elements, the results of performance assessment simulations whose object is to model the release of radionuclides to the biosphere.
Computation fluid dynamics (CFD) simulations were used to model the release of hydrogen from the fuel-cell vehicle and to study the behavior of the ignitable hydrogen cloud inside the tunnel.
An integral combination of design of experiments (DoE), partial least squares regression (PLSR) and response surface methodology (RSM) was applied to model the release of carvacrol into a food simulant from an antimicrobial material based on low-density polyethylene/organically-modified montmorillonite (LDPE/OMM) nanocomposite films.
Concerning the Pavia approach, which can model the release, diffusion and depletion/degradation of candidate signals (e.g. cytokines) travelling in the extra-cellular environment, the good agreement with ad hoc experimental data obtained in our laboratory validated the adopted approach, which in the future can be applied also to other candidate signals.
In our proposed model, the release of phosphorylated Jak2 from the GHR is induced by GH stimulation, after which βTrCP can bind the GHR and select the receptor for endocytosis.
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According to our model, the released GABA activates the extrasynaptic GABA receptors and contributes to the tonic inhibition of neurons.
The answer requires modeling the release and spread of radioactive material through the environment.
In addition, in modeling the release process of gaseous fission products, the Weisman, Booth, Mason, and T.S. models were examined.
Corresponding empirical piecewise defined mathematical functions modeling the release of encapsulated compounds [C t)] using Heaviside functions is given by Eqn. (6).
In modelling the release of three other radionuclides (3H, 14C and 36Cl), the in situ generation and decay are taken into account.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com