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Steinacher and Wright ([2013]) also used a dynamical systems approach and used it to model the regulation of behavioural activation.
In this model, the regulation of translation and the regulation of proteolysis are active.
We here employ the transcription rate to model the regulation function.
In our example model, the regulation at protein level is based on an early model by Tyson [ 46].
Random forests is an example, as is the Bayesian model averaging method previously used to model the regulation of splicing.
In the present work we explicitly model the regulation of alternative splicing and make much better use of the available data.
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There are two problems to be faced in modelling the regulation of FOXO.
Finally, we plan to include the potential influence of circulating factors such as insulin and leptin and eventually "close the loop" by modeling the regulation of food intake in mice.
SIGMOID models the regulation of a gene by a linear combination with soft thresholding.
To the best of our knowledge, stream is to data the only publicly available framework for modeling the regulation of the rate of transcription.
Model 151 is a model of the regulation of that same JAK/STAT pathway by IL-6 in hepatocytes [30].
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