Sentence examples for model the potency from inspiring English sources

In this contribution, we apply the principles of PCM to model the potency of 3,228 compounds on 11 mammalian cyclooxygenases.

In animal models, the potency of single blastomere-derived embryos can be defined by transferring them into the uterus of foster animals.

The conventional model overestimates the potency of CO2 because it applies the strong solar response instead of the weak CO2 response to the CO2 forcing.

9 As mentioned previously, the Simeoni-like model has been adapted to capture differences in response in the translational space with a mixture model to capture the potency; in the clinical space, the heterogeneous response for pembrolizumab was again captured using a mixture model.

So we established a high throughput screen using L6 differentiated muscle cells as a model for evaluating the potency of natural product extracts in inducing glucose uptake.

The CoMFA model accurately predicted the potency of a test set of flavonoids (n = 6), generating a correlation between observed and predicted potency of q2 = 0.825.

The assay involves dissolving the sample in water and using a partial least squares model to predict the potency of the product.

Using an experimentally inspired stochastic model, based on the potency and chromosomal distribution of oncogenes and tumor suppressor genes, we show that cancer cells have evolved to exist within a narrow range of chromosome missegregation rates that optimizes phenotypic heterogeneity and clonal survival.

A murine acne model measuring P. acnes-induced ear swelling and production of pro-inflammatory cytokines in tissue chambers may provide an alternative animal model for evaluating the potency of acne vaccines.

Additionally, hOE-MSCs are an appropriate model for validating the potency of therapeutic agents such as kinetin, a cytokinin that has been shown to increase IKBKAP mRNA and protein expression in FD cell lines and in vivo models [20], [22], [35], [36] as well as in leukocytes of healthy carriers of the FD mutation [37].

Since BIRC6 was not previously evaluated in a neuroblastoma model, we studied the potency of BIRC6 as a potential new target for neuroblastoma therapy.