Sentence examples for model the pathology from inspiring English sources

Therefore, these approaches, though informative, did not accurately model the pathology of anti-MPO-associated SVV in humans.

Because of the bone remodeling that takes place in the multitude of mouse models, the pathology of the bones in these models must be extensively characterized.

Because in biAT mice, our bigenic AD model, the amyloid pathology synergistically promotes tau phosphorylation and tauopathy in limbic regions by activating GSK3 [24], we analyzed AAV-APP.SLA mice for endogenous mouse tau phosphorylation.

While these transgenic mice have proven useful in advancing understanding of how high levels of α-syn interfere with normal cellular function, they fail to model the nigrostriatal pathology and basal ganglia-based motor features of PD.

The first key development is that our data potentially model the "spreading pathology" model of PD championed by Braak.

However, trying to model the entire pathology is seen as an unrealistic attempt (e.g. [ 30, 31]).

iPSCs from these patients can be differentiated into cell types relevant for the disease, representing a useful tool to model the ALS pathology in vitro.

In this rat model, the amyloid pathology at advanced stages (18 20 months) is further accompanied by strong microglial activation and dystrophic neuries surrounding amyloid plaques [ 11].

As we can currently model the vascular pathology of preeclampsia with some success, it is most likely that targeting vascular abnormalities will be the focus of emerging therapies (e.g. statin therapy).

Our system does not model the inflammatory pathology of MS, as although microglia are present, there is no blood supply, and so T and B cell infiltrates are not present.

Virulence is modeled as the pathology of the parasite, or the level of agent or macaque illness required to optimize transmission of the parasite.