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Many geometrical and biophysical constructs are proposed over the years to model the multifaceted nature of protein structural parameters.
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This analysis was then considered, along with the previously collected TRIAD focus group data analyses, to create a conceptual model of the multifaceted impact of diabetes medication across the spectrum of delivery systems.
The results are discussed within the framework of a conceptual model that illustrates the multifaceted nature of executive function and its relationship to self-awareness and everyday functional competence.
We employed this model to demonstrate the multifaceted activity of an oncolytic herpes simplex virus genetically modified to express interleukin-12, G47∆-IL12.
It is clear that chromatin structure and epigenetic mechanisms play a crucial role in determining these gene responses, and in fact the immune system has proved an instructive model for investigating the multifaceted mechanisms through which the chromatin landscape contributes to gene expression programs.
Cross-classified models can account for this hierarchy of the data and model the complex and multifaceted childhood environment (1, 2).
Here, we have demonstrated that 25HC activates the ER-mediated signaling in estrogen sensitive breast and ovarian cancer cells as well as in vascular model systems, hence mimicking the multifaceted estrogen action.
22 Communication is complex and simple models might not solve the multifaceted problems faced by interdisciplinary teams.
Indeed, in 2012 two groups showed that pharmacological inhibition of polyP could prevent thrombosis without increasing surgical bleeding in mouse models [29,30], again emphasising the multifaceted role of the platelet secretome in haemostasis.
To overcome the aforementioned barriers to high-quality care for older adults, the frail older Adults Caree in Transition (ACT) - study introduces the geriatric care model, a multifaceted intervention based on the chronic care model.
We develop and test a model which suggests that ADHD influences entrepreneurship through the multifaceted trait of impulsivity.
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CEO of Professional Science Editing for Scientists @ prosciediting.com