To obtain estimates for linear models, the minimization problem of (43) is easily solved using an iteratively reweighted least squares approach, as described in [32].
An objective of the model is the minimization of development cost, while satisfying the required system and reliability requirements.
The master problem of the two-stage model is the minimization of economic loss for load curtailment under lines reinforcement.
In the present work, an integrated model for the minimization of the operating costs of a cooling water system is developed.
The objectives of the model are: the minimization of costs (material handling inside facilities and between facilities, and re-layout); the maximization of adjacency between departments; and the minimization of the "unsuitability" of department positions and locations.
As we already said in the previous subsections, the optimization model including the minimization of the nodes' total travelled distances along with other possible metrics has been introduced in [8].
Simple point and click manipulations of the model allow the minimization of strain in the phosphate-backbone linkages between these domains and the identification of any steric clashes that might occur as a result.
To solve this max-min model, the inner minimization problem is transformed into its dual problem.
For the NMA of the elastic network model, the energy minimization process is not necessary, and the NMA can be applied to any given conformation (28).
