Sentence examples for model the alterations from inspiring English sources

Mice are not an ideal system to model the alterations of the biomechanical function of the joint that are associated with human OA due to their small size as compared to humans.

For such a model, the alteration of Ca2+ concentration in a cilium is given by: (31) V R ⋅ d [ C a 2 + ] d t = S R z ⋅ F ⋅ I C a 2 + P + I C a 2 + A. By substituting formulas for the passive and active Ca2+ currents into equation (31), one obtains: (32) V R ⋅ d C a 2 + d t = S R z ⋅ F ⋅ - C 0 ⋅ c t ⋅ g 0 ⋅ ν V m, t ⋅ V m - E C a 2 + - β ⋅ C a 2 + K A + C a 2 +.

This mouse model recapitulates the alterations in the innate immune response that contributes to disease triggering in human IBD.

Activation of mutant RB or functional loss of RB and PTEN in the TRP orthotopic model mimicked the alterations observed in human GBM, and allowed us to examine the relative importance of inhibiting the PI3K and MAPK pathways in vitro and in vivo using drugs that are currently in clinical trials for the treatment of GBM (Bendell et al., 2012; LoRusso et al., 2010).

The procedure represents a novel approach in modelling the alteration (naturalness) of tree species composition of forest vegetation.

Hugueney, P. et al. Metabolism of cyclic carotenoids: a model for the alteration of this biosynthetic pathway in Capsicum annuum chromoplasts.

This, together with inclusion of processes of iron corrosion and diffusion, has enabled investigation of a representative model of the alteration of bentonite in a typical EBS environment.

In the neuron astrocyte model (5a - 5i) the alteration of this neural excitability threshold can be reproduced by dynamical changes in (v_{P}), (v_{P'}) and (v_{I}).

One of the difficulties encountered during the development of the experimental model was the alteration in calcium homeostasis caused by the thyroidectomy.

Based on our findings, we propose a model whereby the alteration of NF-κB activity at the early stages of infection with pathological prion protein leads to neuronal cell death mediated by mitochondrial apoptosis.

These data suggest that the suppression of L1-CAM binding by antibody administration can affect the pain hypersensitivity in a partial nerve injury model and the alteration in L1-CAM in primary afferents is involved in the development of neuropathic pain.