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In this study, we created a novel genetic mouse model that selectively expresses functional IL-1R1 on defined cell types under its endogenous promoters.
To learn about the developmental perturbations that lead to these brain lesions, we created a mouse model that selectively deletes the Tsc2 gene from radial glial progenitor cells in the developing cerebral cortex and hippocampus.
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Phenomenology is the attempt to study experience (whether objectively or subjectively) free from entrenched theoretical models that selectively attend to certain features of our experience while ignoring others.
We, therefore, performed experimental metastatic models that selectively address the impact of CXCR3 blockade on the extravasation step of the CRC cells by inoculating the cancer cells into mice through intravenous injections in both the hepatic and the pulmonary models.
Here we generated a mouse model that has selectively lost ERα in either stromal (FSP-ERαKO) or epithelial prostate cells (pes-ERαKO) to determine the requirements of ERα for oestrogen-stimulated prostate proliferation and SQM.
Using a mouse model that lacks MyD88 selectively in DC or in B cells, soluble CpG-B has been shown to augment the T-cell-dependent antibody (Ab) response to protein selectively through DC (Hou et al, 2011).
(i) Under the simple Brownian model that represents a selectively neutral expression evolution (Gu 2004), we have U XY = 2σ t, where σ is the rate of mutational variance.
Additionally, we model end-stop cells that selectively respond to contour terminations.
This particular facet of alcoholism is captured by rodent models that selectively were bred to maximize a penchant for or aversion to ethanol, such as the aptly named high-alcohol preference (HAP) and low-alcohol preference (LAP) mice (Grahame et al. 1999).
A good direction could be building a structured model that introduces the thermal imagery selectively, in order to maximize the BG/FG discrimination.
Experimental diabetes models can be induced by chemicals that selectively destroy the insulin-producing β-cells in the pancreas [ 22].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com