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The substitution model was selected following model testing using Modelgenerator version 85 [ 54].

The model of amino acid substitution used was JTT [ 60] because following model testing using MultiPhyl [ 34] this was the model that was best-fit to the data.

All continuous variables were examined for the best functional form before model testing using the −2 log-likelihood ratio test and visual inspection of plots.

While not a method of demographic inference, the projection's shape provides clues as to the direction of further model testing using formal demographic inference tools, such as dadi (Gutenkunst et al. 2009) or fastsimcoal2 (Excoffier et al. 2013).

The IM method (Nielsen and Wakeley 2001; Hey and Nielsen 2004) is the most commonly used approach for conducting statistical test of speciation models, because it offers a robust framework for model testing using the LRT (Hey and Nielsen 2007) or the AIC (Carstens et al. 2009).

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For initial model creation, we used wildtype temporal activation profiles of MAP kinases and NF-κB and, for model testing, used TRAF6 KO and TRADD KO data.

Before building large-scale installations, the design should be checked out with turbine model tests, using geometrically similar models of small and intermediate size, all operating at the same specific speed.

We conducted model tests using ring-on-disc test configuration and component tests on bearing test rigs.

These findings suggest that dynamic model tests using this ESB model container should be conducted with the container completely filled.

This factor was calculated for each model tested, using marginal likelihood estimated according to the method of Newton and Raftery [29], with the modifications proposed by Suchard et al. [30].

Polymorphisms were codified to test both additive and dominant effects using R to be similar with marker model tested using TASSEL.

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