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The t-values of the minimum adequate model terms remained significant and estimates did not significantly change, indicating that pseudoreplication does not affect our results.
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Five predictors (as derived from significant terms detected in the single lmekin regression models) were incorporated into each global model for HR and GS, although not all terms remained significant when incorporated into multiple regression models (Additional file 3).
Variables and interaction terms remained in the model if they were significant in the model (P < 0.05) or if removal resulted in substantial change to the effect of other variables (10% or greater).
Models were compared using a model simplification approach based on the removal of the least significant terms, using Wald statistics, until only significant terms remained.
Final models were achieved by sequentially dropping the least significant terms based on Wald statistics until only significant terms remained.
This table illustrates the significant terms remaining after reduction of the full model.
In the sensitivity analysis which did not adjust for smoking status and cotinine (model 3), the urinary cadmium term remained non-significant (βCd = −0.0062, 95%CI: -0.0145, 0.0021).
Deal terms remain to be settled.
The terms remain undisclosed.
Terms remain undisclosed.
All other terms remain the same.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com