Sentence examples for model systems suggest from inspiring English sources
The differences observed between the hydrodynamic parameters of the high pressure and model systems suggest that the five dimensionless groups employed are not enough to fully characterize the global bed behavior.
Studies in model systems suggest that longevity can be modulated by changes in gene and protein expression.
Data from model systems suggest that inhibition of the pathway would both arrest growth and induce apoptosis or sensitize the cell to proapoptotic stimuli [3].
These results from genetic model systems suggest that Arf loss can contribute to MM pathogenesis via p53-independent pathway(s), as previously noted in human MM cells [12], and that an intact p53 pathway remains a potential target for the treatment of this highly aggressive, chemo-resistant malignancy.
While preceding models of PTB function suggest a mechanism of splicing repression by obstruction of splice sites or averting interaction with the spliceosome through looping of the pre-mRNA [22], [33], [34], recent data from the Fas and c-src model systems suggest a more complex mechanism [36], [37].
Recent data from model systems suggest that MMPs are involved in breast cancer initiation, invasion and metastasis.
The improved localizing and clearance characteristics of chimeric 81C6 in xenograft model systems suggests that chimeric 81C6 would be an improved reagent for intracompartmental therapy of tenascin-expressing tumors in the human central nervous system.
Our finding that downregulation of Gata2 is a common feature for two AML mouse model systems suggests that abrogation of a Gata2-dependent transcriptional program may contribute to leukaemogenic transformation which is supported further by low GATA2 expression found in large-scale human AML datasets.
Genetic modulation of AMPK activity in various model systems suggests that AMPK may represent an underlying mechanism to increase longevity as a consequence of dietary restriction [6], and also that AMPK activity may be responsible for the benefits of exercise [7].
However, accumulating evidence from different AD model systems suggests that tau is actively secreted and transferred between synaptically connected neurons.
These findings are consistent with findings in S. cerevisiae and other model systems, suggesting that mammalian sirtuins can play both protective and proaging roles [ 76].
