Sentence examples for model systems representative from inspiring English sources
Our understanding how these pathogens are able to infect their host plants will benefit greatly from information obtained from model systems representative for plant- Phytophthora interactions.
The goal of this study is to perform these types of calculations for model systems representative of various levels of subcellular organization and to compare the results with observations and measurements reported in the literature.
The Escherichia coli multidrug transporter AcrB [24], which in its native trimeric state has an approximate size of ~ 360 kDa, was used as a model system, representative of many transport proteins.
Based on the preservation of mRNA expression profiles that are characteristic for the histological subtype we propose that these model systems are representative for the primary tumor from which they are derived.
In this study, we aimed to compare gene expression profiles of osteosarcoma biopsies with cell lines and xenografts, in order to investigate whether these model systems are representative for the primary tumor.
As osteosarcoma xenografts and cell lines still express histological subtype-specific mRNAs that are characteristic of the primary tumor, these model systems are representative for the primary tumor from which they are derived, and will be useful tools for studying mRNA expression and pathways important in high-grade osteosarcoma.
The PC research field has long been hampered by the limited availability of representative model systems.
We therefore endorse that, despite biological differences, both xenografts and cell lines are representative model systems for studying mRNA expression in high-grade osteosarcoma.
JURKAT and U937 cells were chosen as representative model systems that recapitulate the different biological responses of the cell lines tested.
In addition, functional characterization in model systems may not be representative of in vivo human physiology and an observed difference in a model system may not be of clinical importance.
Furthermore, the drug response in these models shows a good correlation with the primary patient tumors [ 5, 6, 11], and altogether the xenografts are representative model systems for studies of metabolic and genetic patterns in human breast cancer.
