Sentence examples for model systems rather from inspiring English sources

Moreover, scientists can now choose to study their specific questions using the most suitable model systems rather than being limited to a handful of laboratory strains that are limited in their ability to model human diseases.

Often, because of this limitation, pharmacogenomics researchers focus on functional validation of associations in cell lines (Welsh et al. 2009; Duan et al. 2009; Huang et al. 2007; Matsson et al. 2012; Ingle et al. 2010) or model systems, rather than replication of effects.

We note that we used a HeLa cell-based model system rather than lung cancer cells for two main reasons.

The abstract has been revised to clarify stress-induced PKR activation as the first described rather than the primary function of PACT, as well as to highlight the genetic utility of Drosophila as a model system, rather than merely suggesting that additional model systems are required.

To arrive at an approach also feasible in an industrial setting, all QTAIM calculations were done with small-model systems rather than full active sites.

Previous studies on DLC lubricated contacts have tended to use model oil systems rather than fully formulated lubricants and from this an interesting picture of lubrication mechanisms is emerging.

Interestingly, preclinical evaluation of monoclonal antibody therapy with bevacizumab and/or cetuximab has not been conducted in a syngeneic model system, but rather in xenograft systems [ 28, 85].

Since the authors solved the crystal structures of NP7 at low (5.8) and high pH (7.8) and in NO-bound form, for MD simulations these structures could be used to model the molecular systems rather than using NP4 structures.

Many biological systems of interest exhibit a nonlinear dynamic behavior which makes the analytical solution of models representing such systems rather complicated, if not impossible, for most of the realistic situations.

Having rare, high penetrance mutations is a significant breakthrough, as it makes possible the development of model systems based on biology rather than on clinical symptomatology.

These ideas are discussed in detail in the following chapters and it is clear that plants are rather easier model systems to work with here than animals partly because of the speed of change [Feldman & Levy] and that there is a great deal more to be learnt from symbionts [Gilbert ]