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The network size for the model systems is 10,000 nodes.
Regardless, the primary mechanism underlying IDH-induced oncogenesis in several model systems is a block in cell differentiation (Pirozzi et al., 2013).
Finally, the effect of size and characteristic lengths of representative material element (RME) on the extent of damage in the model systems is investigated.
Progress with experimental model systems is becoming an important asset to understand virus behavior in the more complex environments faced during natural infections.
Mammalian disease models offer in vivo opportunities and extensive similarity to the human brain, but testing the therapeutic value of small molecules in mammalian model systems is extremely expensive and requires time-consuming experimental designs that can be prohibitive.
Understanding the biodistribution of drugs and their partitioning in model systems is essential for the design of drug delivery concepts, but it is often difficult or impossible to obtain such information by conventional methods.
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Some examples of the model systems are introduced.
Two different model systems were studied: a polymer melt (silicone oil) and a molten (borosilicate) glass of comparable viscosity.
In order to reduce this inherent complexity of mixed oxide catalysts, suitable model systems are sought.
With advances in technology made possible through research funding from The ALS Association, different approaches to minimize the use of these model systems are being developed.
In this situation, experiments on simple model systems are required.
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