Sentence examples for model systems generally from inspiring English sources

However, with the notable exception of mouse, current transgenic model systems generally rely on the random integration of transgenes into the recipient genome.

Because of high success rates, the fly and worm (D. melanogaster and C. elegans) model systems generally use large double strand RNAs (dsRNAs) of 300 800 bp.

Having shown that carnosine can react with protein carbonyls, thereby generating "carnosinylated" polypeptides using model systems, 41 it might be generally proposed that similar adducts can be generated in senescent cataractous lens fiber cells exposed to carnosine during the therapeutical treatments with 1% NAC lubricant eye drops in vivo.

Plasmid DNA (pDNA) vaccines are effective at eliciting immune responses in a wide variety of animal model systems, however, pDNA vaccines have generally been incapable of inducing robust immune responses in clinical trials.

Model systems for gene amplification have generally relied on dominantly selectable enzymes such as DHFR and CAD [ 3, 17].

Ignoring the correlation effect when modeling the reliability of multistage systems generally results in inaccurate estimation of the overall system reliability and inefficient operations policy accordingly.

The structure of these health systems generally reflects a model of health care response to acute episodes of illness.

Although it is still debated whether the small oligomers or the large inclusions are more toxic, the overall evidence from model systems strongly suggests that aggregate prevention generally results in disease amelioration.

We focus on freshwater pulmonate snails of the genus Physa, which by virtue of their reproductive plasticity, ease of culture, and availability of genetic markers have become important models for the study of mating systems generally [ 34- 36].

Assessing reliability analysis of engineered systems generally requires consideration of model uncertainty due to lack of knowledge (also known as epistemic uncertainty).

The specific needs of girls in (juvenile) justice systems, generally premised on male models, should be taken into account.