Sentence examples for model systems established from inspiring English sources

Using cellular model systems established from two independently derived MCF-7 cell lines overexpressing aromatase activity, we examined the effect of GP88 on letrozole responsiveness.

In addition, mouse model systems established using cancer cell lines confirmed the results obtained in in vitro assays and further established the role of miR34a as a tumour suppressor (Pramanik et al, 2011b; Kasinski and Slack, 2012; Kumar et al, 2012; Li et al, 2012).

Further use of the model system established here might therefore yield new insights into the vulnerability of the axonal compartment to aSyn toxicity, and into the relationship between axon degeneration and cell death in neurodegenerative diseases.

In addition, the model system established in our study may become a useful platform for functional studies of putative molecular mediators of ploidy duplication, which could be explored as potential new targets for prophylactic cancer therapy to prevent metastasis.

Additionally, genetic evidence in the mouse and ES cell model systems has established that the expression of Myf5 and MyoD genes depends exclusively on the HAT activity of p300 [ 43].

To bridge the gap between the embryonic and postembryonic lineage model systems, we established an alternative approach: By adapting the Flybow system (Hadjieconomou et al., 2011; Shimosako et al., 2014) we were able to label primary lineages in a way that allowed their identification and documentation in the VNC of living embryos (Fig. 1A,B).

A numerical model system was established for the emergency response of a nuclear accident over complex terrain.

The model system was established by covalently linking glucose oxidase (GOD) onto the inner wall of the nanochannels of the porous anodic alumina (PAA) membrane.

For the case of TiN as a model system, we established the preferred slip systems for edge and screw dislocations, with a Burgers vector of a/2〈1 ¯1 0〉 on the {0 0 1}, {1 1 0} and {1 1 1} slip planes.

To test whether GABAARs can play a direct role in synaptic target recognition, a novel co-culture model system was established.

A model system was established by eight serial dilutions of the malignant B-cell lymphoma cell line, OCI-Ly8, into the embryonic kidney cell line, HEK293, prior to parallel analysis by exon microarrays and tag-seq.