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The development of novel embryo-derived model systems, combined with methods that examine chromatin status and chromosome conformation, led to deeper understanding of the process of Hox activation in the early embryo.
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Model systems combining different defects were also explored, including a defect-anchored metal system, a bilayer graphene system and a grain-boundary system.
The power and popularity of zebrafish as a forward and reverse genetic vertebrate model system, combined with its small size, have made it an ideal model in which to study the genetics of histologically scorable phenotypes.
The Xenopus model system combines electrophysiological rigor with a cell type that does not express mammalian PC2, a protein shown to affect PC1 cleavage and expression of PC1 cleavage products [26], allowing a clear picture of any role PC1 cleavage products may have in regulating SOCE.
The Extended UNIQUAC model for electrolyte systems, combined with the Soave Redlich Kwong equation of state is used to describe the complex vapor liquid solid equilibria of sulfur dioxide in electrolyte solutions.
These results suggest that the application of GWA approaches using cell-based model systems, when combined with complementary functional validation, can provide insights into mechanisms responsible for variation in cytidine analogue response.
A full simulation model was developed for absorption cooling systems, combined with a stratified storage tank, steady-state or dynamic collector model and hourly resolved building loads.
In contrast, experiments in simpler systems combined with thermodynamic models provide a powerful tool to understand the melting chemistry in the multi-component system.
Further empirical data from natural systems, combined with theoretical models incorporating condition-dependent extrinsic mortality, are needed to test the above ideas and to better understand recent exceptions to the classic ETS.
We are using Ptolemy II as a rapid prototyping laboratory to model systems that combine cloud services, wireless sensor networks and handheld interfaces.
These lipids have the capacity in model systems to combine with cholesterol to form domains, which has led to suggestions that they could contribute to protein sorting in the Golgi.
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