Sentence examples for model systems but from inspiring English sources

Despite the extensive attention on the factors that determine the specific packing of SSEs in certain forms, most of the above discoveries were made in simple soluble model systems but not natural proteins.

This study used GRPr-targeted radiopeptides and a GRPr-positive xenograft model as model systems, but we assume that the results also apply to other (radio peptides that target receptors highly expressed on solid tumors.

Hsp90 has been studied widely in animal and yeast model systems, but little is known by comparison about plant Hsp90.

These findings also help to reconcile the disparate findings that immune therapeutic approaches can be used successfully in preclinical model systems but have yet to achieve successful responses in the vast majority of patients by demonstrating the importance of the tumor hypoxic environment in markedly inducing the immune suppressive properties of the GBM.

On one level, individual genes can be prioritized for analysis by gene knockdown in animal model systems, but we also hope that the dataset can be utilized to revisit previously generated gene knockouts in mice to screen for subtle defects in orofacial formation and function that may not have been recorded.

Cell lines are critical model systems but cell line annotations have been heterogeneous and sparse.

Escherichia coli finds extensive use as a model system, but has not been widely used as an industrial host.

Therefore, signaling through the IFN-γ receptor may directly or indirectly influence IL-17A production in our model system, but is not entirely responsible for IL-17A production.

Therefore, some F. tularensis factors required for virulence in mammals are also required for virulence in the arthropod model system, but there are distinct molecular differences utilized by F. tularensis to exploit the two hosts [22], [23].

Disrupting microtubule organization eliminated such peripheral localization of DMs in this model system, but it did not affect their association with chromosomes, indicating that a microtubule-mediated antipolar force would be responsible for the mitotic fluctuation of DMs.

The presence of differential signature gene expression in in vivo data suggests that relative expression of oxygen-responsive genes is not simply a consequence of the adaptation of NZM tumour cells to culture in our model system, but is likely a snapshot of prevailing transcription at the time the tumour sample was removed.