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The Escherichia coli multidrug transporter AcrB [24], which in its native trimeric state has an approximate size of ~ 360 kDa, was used as a model system, representative of many transport proteins.
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Our understanding how these pathogens are able to infect their host plants will benefit greatly from information obtained from model systems representative for plant- Phytophthora interactions.
The goal of this study is to perform these types of calculations for model systems representative of various levels of subcellular organization and to compare the results with observations and measurements reported in the literature.
Based on the preservation of mRNA expression profiles that are characteristic for the histological subtype we propose that these model systems are representative for the primary tumor from which they are derived.
In this study, we aimed to compare gene expression profiles of osteosarcoma biopsies with cell lines and xenografts, in order to investigate whether these model systems are representative for the primary tumor.
As osteosarcoma xenografts and cell lines still express histological subtype-specific mRNAs that are characteristic of the primary tumor, these model systems are representative for the primary tumor from which they are derived, and will be useful tools for studying mRNA expression and pathways important in high-grade osteosarcoma.
In this work, therefore, we investigated a model system as the representative surface-bound polymerization.
As one example, LPCMO is chosen as a representative model system due to its sub-micrometer scale phase separation that can be easily accessed by conventional lithographic fabrication processes.
Preliminary tests on a representative model system suggest that standard step size values used at present are lower than necessary for accurate sampling.
However, further investigations are needed to assess whether X. laevis can be used as a representative model system for other species, too.
The results from the GPCR model system were thus highly representative of the general gene regulatory network in human cells.
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