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The minimal model system presented here mimics in vitro the hyaluronan-modulated early stages of cell adhesion, and demonstrates that the presence of a polymer cushion influences both the final equilibrium adhesion-state and the spreading kinetics.
For the model system presented in this paper, it is found that a modified Randles circuit best models the data when no BSA film is present, and that an additional time constant (resistor and constant phase element in parallel), modeling a porous, insulating film, is needed when a BSA film is formed on the electrode surface.
The Drosophila model system presented in this work reveals some of the consequences of UPR activation when lysozyme is overexpressed in the fly.
Importantly, the experiments performed suggest that TIMP-1 inhibitors could represent a novel treatment as a chemosensitising approach given before conventional therapy and the model system presented here offers the opportunity to investigate this hypothesis.
Through their action, halogenases can convert simple amino acids into unique building blocks; in the model system presented by the kutzneride cluster, we see a broad display of Nature's halogenation strategies.
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While critical for discerning fundamental cancer mechanisms, model systems present both opportunities and challenges for translational medicine practitioners.
Validation of the fluctuations in surface temperature and O3 concentrations simulated by MM5 and CMAQ showed good agreement with 1990s observations (Hogrefe et al. 2004); hence, the integrated model system presents a useful method for studying regional climate-related changes.
Analytical and therefore general quantitative criteria identifying the regions of multiplicity for the model system are presented.
In this paper, some experimental findings on the time and pH dependences of U accumulation obtained in a pilot plant model system are presented and discussed.
The further demonstration by simultaneous detection of human immunodeficiency virus (HIV) and hepatitis C virus (HCV) in one channel as a model system is presented in this essay.
In Section 5, we investigate the direction and stability of Hopf bifurcation by applying the center manifold method and the normal form theory. Numerical results for the proposed model system are presented in Section 6.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com