Sentence examples for model system expressing from inspiring English sources
An in vitro cell culture model system expressing enhanced green fluorescent protein (EGFP) was used to develop the assay, which was based on the intracellular quantification of a full-length double-stranded Dicer substrate siRNA by stem-loop RT qPCR.
Binding assays, in a cell model system expressing human LOX-1 receptors, confirm that PLAzPC markedly inhibits ox-LDL binding to LOX-1 with higher efficacy compared to previously identified inhibitors.
A transient mouse model system expressing viral structural proteins in the liver was constructed using the hydrodynamic transfection method to confirm in vivo anti-HCV activity of the selected siRNAs.
For example, mechanics of human pancreatic adenocarcinoma cells (Panc-1), a cellular model system expressing mainly keratin 8 and 18 as intermediate filaments, are highly dependent on the cell's keratin cytoskeleton organization.
Therefore to address this issue, we developed a model system expressing inducible mutant SPOP in mouse prostate organoids.
The objective of the work described here was to develop an in vitro experimental model system expressing transcription repressors at different levels and verify whether this approach might be useful in identifying HbF inducers acting on these γ-globin gene regulators.
This evidence could represent an important clue to understanding the formation of pathological FUS inclusion during the progression of ALS, and it implies that the study of pathological FUS should be carried out in cell model systems expressing physiological levels of mutated proteins.
To develop this cancer model, a transgenic BAC system expressing eGFP linked to oncogenic KRAS G12V in zebrafish pancreas under control of ptf1a promoter elements was generated.
The human T cell line Jurkat was used as a model system to express the anti-CEA CIR and to test their ability to initiate T cell activation in response to tumor specific cell surface antigen.
The serum-activated fibroblasts in this model system uniformly expressed syndecan-1 (Fig. 1g).
For these studies, we chose glioblastoma U87 as a model system, which expresses LRP1 in abundance in vitro, and examined the brain biodistribution pattern of ANG1005 and Angiopep-2 bearing human glioma xenografts.
