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However, our model suggests somewhat higher overall tOPV vaccine needs than currently planned to ensure high enough population immunity to transmission everywhere at the time of OPV2 cessation.
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However, purely statistical 'surface models' can be unreliable for long-term extrapolation, and a more biologic 'deep model' suggests a somewhat different picture, especially for the ER+/PgR+ subgroup.
This latter is known to be required for binding of p73 to p300 [ 62] and our model suggests that the picture is somewhat similar to that seen in p53.
Our model suggests that the referendum paradigm is slightly more likely to win out, as it did under somewhat similar circumstances in 1980.
But Dr. Hall's model suggests otherwise.
The model suggests two independent predictions.
The dominant mammalian model suggests ∼2 glomeruli/OR.
Direct measurements of FDG uptake in a case study suggested somewhat higher doses than are currently provided in standard models [ 26].
A sense of personal virtue, you might suggest, somewhat sheepishly.
When comparing the expression change in the ancestral population to the expression difference in either evolved population, there was a slight reduction in the slope term of the linear model, suggesting that many genes are somewhat less responsive to environmental change.
These estimates are close to those of the IBD and IBD + IBS model, suggesting that explanation (2) is more likely than (1), although the IBD and IBD + IBS model seem also to overfit the data a little (since their estimates of σ e 2 were somewhat lower than those of the pedigree based model).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com