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If alignment approaches are used to produce the model structures, also the alignments and in particular also the used templates are known and can directly be used.
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This new model structure also suggests that two of the three regions need completely opposite control actions.
The model structure also allows a comparison of an early awareness campaign and a campaign designed to increase screening uptake.
YscD model structure also includes the transmembrane (TM) domain and the N-terminal cytosolic part of YscD.
The model structure also incorporates the costs and outcomes of cardiometabolic consequences of treatment with each AAP.
The model structure also allows a natural incorporation of other epigenetic processes to investigate their regulatory roles in acquired antiestrogen resistance.
The model structure also cannot fully capture the heterogeneity of TB epidemics (for example, those driven primarily by HIV) and the complexity of a diagnostic ecosystem with a large, poorly functioning private sector alongside the public sector as present in India [ 4244]4244]
The model structure also allows the impact of different rates of disease progression in the infant [ 22- 24], the additional benefits to the mother and infant from early diagnosis, the cost of caring for a child with HIV and AIDS [ 30, 31], the medical costs of a child with HIV and AIDS and the impact of rapid testing [ 18].
This model structure also described data from NSCLC patients treated with carboplatin/paclitaxel alone or in combination with bevacizumab or motesanib [ 20], as well as data from renal cell carcinoma (RCC) patients treated with sorafenib [ 21], where the tumour natural growth was first characterized using data from placebo-treated patients.
In principle, molecular dynamics (MD) simulations can be used to refine protein model structures and also to model loops in homology modeled protein structures, but it is limited by the currently accessible simulation time scales.
Selection between alternative model structures can also be performed at this step.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com