The positions of the characterized resistance mutants in the model structure identify two promising regions for the design of fusion inhibitors.
Analyzing the assessment reveals gaps and inconsistencies concerning data selection (ultimately relying on a small number of short-term studies only), data synthesis (pooling of heterogeneous study designs and clinical endpoints), and economic model structure (identifying double-counting of nonresponders as a likely source of bias, alongside further methodological anomalies).
These census areas define the subpopulations of the metapopulation modeling structure, identifying 3,362 subpopulations centered on IATA airports in 220 different countries.
The model structure is identified with the help of a heuristic search strategy.
Considering both the genetic structure identified herein (in model As6 and when considering each sample separately for A. germinans) and the a priori scenarios, namely models Ag1 and As1, based on previous studies [ 17, 18, 20, 25, 26, 40], we observed different indications of recent demographic expansions in both species from both the a priori and a posteriori hypotheses.
The cluster analyses as implemented by structure identified the most probable model as K = 2.
We therefore provide a method that determines the sensitivity of community stability to model structure, and identifies the relative role of particular direct effects, indirect effects, and feedback cycles in determining stability.
Use of the reduction software facilitated a syntactical analysis of the model structure to identify variables which had a technical or operational function in the model code.
Using the concept of sign consistency, possible places in the network structure that cause observed discrepancies between experimental data and model structure can be identified, and, furthermore, one can identify changes in the network structure (i.e., adding/removal of certain edges) to minimize these inconsistencies [ 64], (Melas et al. 2013, under revision).
We discuss to which degree the posterior BMA mean outperformed the prior BMA mean and all individual posterior models, how informative the data types were for reducing prediction uncertainty of actual evapotranspiration, and how well the model structure can be identified based on the different data types and subsets.
