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Selected model strains of phototrophic cyanobacteria have been genetically engineered for heterologous expression of numerous enzymes.
The strains used in this analysis were model strains of the genera Rhizobium, Sinorhizobium (syn. Ensifer) and Agrobacterium.
Thus far, two unicellular model strains of cyanobacteria have mainly been used in these studies, Synechococcus sp. PCC7942 and Synechocystis sp. PCC6803 (from now on Synechocystis 6803).
Model strains of cyanobacteria have been modified to overproduce a wide variety of products, including sucrose, 2,3-butanediol, and ethylene; however, none of these photosynthetically produced products have been at a rate that is economically viable.
A similar theme emerges from an observation that has also been described recently using the murine CMV model: strains of mice where NK cells negatively regulate adaptive immune responses do so by the rapid control and removal of antigen (i.e., CMV) [ 29, 31].
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Moreover, a model strain of Chlorella vulgaris is cultivated in the PBR and the volumetric power is analyzed with a classic model, and then the aeration is optimized.
Methylobacterium extorquens AM1, a model strain of methylotrophic cell factories using methanol as carbon source, is of interest because it produces abundant coenzyme A compounds capable of directing to synthesis of different useful compounds from methanol.
Introduced in groundwater samples as vegetative cells, the model strain of B. cereus ss primarily died rapidly; however, a small part remained viable over time.
However, while substantial knowledge is available for several model strains, the diversity of cyanobacterial metabolism remains poorly understood.
Interestingly, swarming motility of both model strains was decreased by 100 μM concentrations of SIM, LOV and MEV compared with a dimethyl sulfoxide vehicle control (Figure 1a).
In recent decades, metabolic engineering of model strains, and process optimization for malic acid production have been rapidly developed.
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