13 The injection of anti-CTLA-4 antibodies in mouse models stimulates the rejection of murine tumors such as colon, ovarian, and fibrosarcoma models, but can also lead to lymphoproliferative disease and autoimmunity in other organs.
The fall of the Laplacian model stimulated scientists to find a replacement for it.
The hBD-2 production) in a reconstructed skin model stimulated with proinflammatory cytokines was used estimate the concentration in the epidermal compartment in vitro, as an approximation of the concentration in psoriatic epidermis.
His highly idealized model stimulated a large amount of work which eventually led to the observation of Turing patterns in open chemical reactors [7], [8].
The highest non-cytotoxic concentrations of auraptene and lacinartin that can be used to evaluate their effect on the inflammatory response of a human macrophage model stimulated with LPS were 25 and 50 μg/ml, respectively (data not shown).
Further, the addition of fibronectin to Matrigel in a 3D culture model stimulated mammary epithelial cell proliferation and increased acinar size [ 43].
For example, induction of Myc in a transgenic mouse lymphoma model stimulated surrounding macrophages to secrete TGFβ, which resulted in induction of cellular senescence [ 54].
Kouji et al. [8] reported that the horizontal integration model is more desirable than the vertical model to stimulate the market for M2M services and that, in the horizontal model, a common M2M service platform is needed to continue collecting information on various devices and to be able to manage and control them.
In Architecture-Engineering-Construction, BIM is the development and use a computer software model to stimulate the construction and operation of a facility, to make decisions and to improve the process of delivering the facility.
Word perception was simulated in the model by stimulating the auditory cortex (Area 1) of the trained network with the well-learnt patterns used for the training (see previous section); pseudoword perception was simulated by presenting new, 'unknown' patterns, built as random combinations of sub-parts of learnt patterns (see Appendix B for details).
