"I'm guessing it has a lot to do with our environment and how special our planet Earth is?" Tyson Beckford, the pillow-lipped male model, speculated, when asked about the rare earth connection.
Because previous studies, as well as our own observations, suggest that human RMS cells do not respond to murine HGF gradients in chemotactic assays and murine HGF cannot stimulate the migration of human RMS cells in an in vivo murine model, we speculated that a different mechanism mediated the reduced metastatic ability and lowered short-term engraftment potential of shMET RH30 cells.
Several models speculate on how such transcriptional gene fusion may have a physiological role.
Current models speculate that lamellocytes, plasmatocytes and crystal cells are distinct lineages that arise from a common prohemocyte progenitor.
Since Nox4, known to be induced by UPR [5] [7], strongly inhibits PTP-1B [49], [49], one can speculate a model in which suppression of Nox4 by proteasome inhibition allows PTP1-B to potentiate IRE1α and consequently XBP1 activation, within a proapoptotic scenario.
For the gas emission system of the 2014 eruption, we speculate a similar model with magmatic fluid input from the depth that triggered the eruption and sustained evaporation of the hydrothermal system.
Given the lack of effect of oral prednisolone on airway inflammation in this model, we speculate that a higher dose of inhaled fluticasone propionate, or given for a longer duration, also would not have inhibited airway inflammation in this acute model of lung neutrophilia, but this remains to be studied.
A fold-back binding model was speculated in which the planar phenoxazone inserts at the GTC site with a loop-out T base whereas the G base at the 3′-terminus folds back to form a basepair with the internal C and stacks on the opposite face of the chromophore.
Based on recent findings with a Wistar rat model, we speculated that the γ-secretase pathway may be associated with atherosclerosis.
This study's findings supported the proposed theoretical model, which speculated that the socially-cohesive neighborhood might lead to a tightly-knit community, which would increase supportive relations.
