Indeed, in the experimental autoimmune encephalomyelitis (EAE) model, a significantly augmented disease progression of Nr2f6 knockout mice establishes a critical and non-redundant functional threshold mechanism of NR2F6 for repressing Th17 cell pathology both in vivo and in vitro [ 57].
After the expansion of human VPC-derived EC and MC, when intra-arterially administered, these cells significantly augmented neovascularization in an animal model of experimentally-induced hindlimb ischemia, compared to human peripheral blood and umbilical cord-derived EPC (pEPC and uEPC).
While SGI-1776 induced moderate levels of apoptosis, it significantly augmented sunitinib-mediated apoptosis in both xenograft models.
In several different murine models of immunotherapy for lung cancer, DMXAA-induced macrophage activation significantly augmented the therapeutic effects of immunotherapy.
Surprisingly, we have found that independently of the model used and basal levels of energy substrates, moderate excess of pyruvate significantly augmented osteoclastogenesis.
While probabilistic extensions to sequence alignment, such as profiles and Hidden Markov Models (HMMs), can capture position-specific variation in multiple alignments, and typically demonstrate significantly augmented sensitivity, all alignment methods remain prone to similar limitations.
In addition, IL-17 production was significantly augmented by T cells recognizing type II collagen in a collagen-induced arthritis model [ 27].
We found that the TM silencing vector significantly augmented the invasive ability of cells detected in cellular invasion assays and mouse orthotopic models.
After its nitrosylation, the protein interaction of GAPDH and Siah1 is significantly augmented.
PRO ingestion also resulted in significantly augmented fat utilization 30 and 60 min post exercise.
