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In the selective binding model, selectivity of target gene activation and repression takes place at the level of DNA-binding.
Although the BCM rule was developed to model selectivity of visual cortical neurons, it has been successfully applied to other types of neurons.
These results are consistent with adaptive biasing force analysis of K+ permeation using a model selectivity filter in wild-type and mutated channels.
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The fitness approach predicted that thymidylate synthase was equally detrimental for both models (selectivity score=1).
Extensive sampling, such as that used here, is very important when modeling selectivity in enzymes, as has been shown in recent studies.
These models (models 2 4, Table 5) never fit the data better than models including predator selectivity (models 5 7, Table 5), suggesting that environmental factors other than predation did not drive the among-population variation in senescence rates.
"This evolutionary ethic that inevitably takes as its key concept the model of selectivity, that is, the struggle for survival, the victory of the fittest, successful adaptation, has little comfort to offer," he wrote.
Using the data obtained from GC and the mathematical relations (that will have provided), the model of selectivity of the products are determined.
C26 colon carcinoma of mice transplanted to the foot was used as a model for selectivity assessment.
We used a bivariate probit model with selectivity correction to estimate the correlates of participating in PA and meeting the recommended level, given participation.
In addition, we investigate tNTS activity in the MCF10A breast tumour progression model, demonstrating selectivity for well-progressed tumour phenotypes and highlighting its potential for use in specific anti-cancer treatments in the future.
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