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Here, we infected Diversity Outbred (DO) mice with ∼100 bacilli by aerosol to model responses in a highly heterogeneous population.
We envisaged that a focus on Ghana and Cameroon would: (1) provide insights for countries with similar socio-economic status and burden levels; and (2) focus attention on challenges and model responses in the West African region.
However, it is accepted that there are some limitations in using aged mice to model responses in elderly humans, as not all age-related changes can be modeled accurately.
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The model response in tension, uni-, bi- and triaxial compression is compared to experimental results.
Comparison between spring-supported sectional model response in wind tunnel and numerical simulation is shown.
(3) Scale-down verification, numerically comparing the model response in the proposed scale-down simulator with large-scale CFD response.
According to the model response, in order to achieve a higher dye removal, an acidic pH and a moderate dye solution concentration are recommended.
The dashed red lines show sutures, YZS and BNS Fig. 4 Measured apparent resistivity and impedance phase and 3D model response in the horizontal pseudo-slice format at different periods for Z xy.
As the evaluation of the complex model framework is computationally expensive, the granulation process is approximated with response surfaces in the studied example, allowing the quick computation of the model response in the optimisation procedure.
The model parameters were chosen so that the global model response in the form of load-crack mouth opening displacement curves were in agreement with experimental results reported in the literature.
Our aim is to determine the model response in various parameter regimes and observe the long term effects of simultaneously changing the values of these two parameters on beta cells.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com