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Model predictions obtained by finite element simulations compared very well to the experimental data and therefore the model relevance for computer assisted application design was assessed.
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This suggests that our animal model has relevance for investigation of fetal overgrowth mechanisms in humans.
Thus, another animal model of relevance for AD but without Aβ overproduction was studied (human apoE4 and apoE3 target replacement mice).
Thus, a similar impairment of leptin signalling is occurring independently of Aβ, in an alternative animal model of relevance for AD pathology.
13 We conclude that our animal model has relevance for the investigation of the effects of transient maternal hyperglycaemia on offspring development and health.
The model has relevance for application for future climates, since it is linked to weather, and allows for an improved understanding of how change in climate in the San Diego Region could impact respiratory health.
A first round of comparisons between MINIDEX data and Monte Carlo predictions obtained with a GEANT4-based package for two different sets of physics models of relevance for neutron production by muons is presented.
Do these mouse models have relevance for human disease?
The large range of features provided by BioModels Database allow users to quickly locate models of relevance for them, analyse them (and understand their structures), simulate them, extract submodels, or download them in various formats (whether text-based or graphical).
In addition, the cellular localization and distribution of leptin and leptin receptors (LepR) were studied in hippocampus and frontal cortex from patients with AD and control individuals, as well as in mice models of relevance for AD pathology (Tg2576, apoE4 and apoE3).
The result of this study is a model for relevance evaluation for an engineering masteŕs program in Peru.
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