This study presented promising approaches such as the concept of local similarity patterns (LSP) and the use of continuous positive and negative weights modeling relevance and undesirability of visual features.
Inferring "biological relevance" from "model relevance" when modeling technique has an influence on the features in the model is then questionable.
In order to address the model "relevance trilemma" – balancing complexity, uncertainty and sensitivity, a global uncertainty and sensitivity analysis (GUSA) was conducted on these five levels of algorithm complexity.
Model predictions obtained by finite element simulations compared very well to the experimental data and therefore the model relevance for computer assisted application design was assessed.
Numerous authors have discussed the potential of BDA for IS research, for example, Shimueli and Koppius [8] described six roles for predictive analytics: generating new theory, develop measurements, comparison of competing theories, improvement of existing models, relevance assessment, and assessment of the predictability of empirical phenomena.
This model offers relevance and flexibility by allowing individuals to make sense of their health experience; however, the contradiction of feeling well yet needing vigilant care may impose confusion, ambivalence and health risk [ 21, 22].
However, although such approaches provide key insights into the mechanisms of stem cell maintenance in transgenic animal models, their relevance and application to human tissues is unknown.
In this study, an animal trial is carried out to test the model's physiological relevance and performance in both healthy and ARDS lungs.
The manuscript has the potential to be stunning and impactful, adding to our understanding of muscle and tendon development and function in the zebrafish model, and has relevance and implications for the study of human muscle/tendon disease and injury.
Another issue is that data derived from global approaches can be interpreted in multiple ways depending on the experimental or theoretical model used, rendering relevance and applicability to mammalian cells somewhat questionable.
