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Model refinement continued until the model was capable of simulating accurate growth and product formation.
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Model building and refinement continued iteratively until all interpretable electron density was modeled.
This refinement continued until transcript 9 with no further adjustment required thereafter.
Refinement continued until Rfree and the crystallographic R factor could no longer be improved.
Improved information on chemical production and usage and addressing key sources of uncertainty such as biotransformation and environmental degradation HLs and continued model refinement are required to improve chemical screening and prioritization efforts.
Sustained investment will enable engineers to continue model refinement and the development of novel applications, specifically targeting increases in precision, personalisation and speed.
Small glitches and refinements continued into spring.
Manual curation of metabolic models often continues over several iterations of simulation-based hypothesis generation, experimental validation, and model refinement to improve quality and predictive accuracy.
b, Validation of the model refinement protocol.
d, Validation of model refinement protocol.
This file contains Supplementary Table 1 which shows the EM data collection and model refinement.
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