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Manual model rebuilding was performed in Coot (Emsley and Cowtan 2004), and maximum likelihood refinement was performed using REFMAC5 (Murshudov et al. 1997).
The final model rebuilding was performed using COOT (Emsley and Cowtan, 2004) and the protein structure was refined with PHENIX (Adams et al., 2002) using NCS and stereochemistry information as restraints.
Manual model rebuilding was done with Coot [62], and structure refinement and the addition of waters was done with CNS [63].
The final round of model rebuilding was guided by the use of simulated annealing composite omit maps followed by crystallographic refinement in CNX 2005 [30] to generate the final molecular model.
Model rebuilding was carried out using Coot [ 34].
Manual model rebuilding was conducted in COOT, and crystallographic refinement was performed in PHENIX51.
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Therefore, the cost of ARIMA model rebuild is composed of two parts, the computation cost of ARIMA model and the transmission cost of ARIMA model parameters.
Model inspection and rebuilding were performed using the program WinCoot 0.7 [19] and further isotropic refinement was carried out with the program PHENIX [20].
Manual rebuilding was performed in Coot (Emsley and Cowtan, 2004).
The model rebuilding and refinement were carried out with COOT [38] and refinement using REFMAC [39].
Four mechanisms that were not included in our model but are likely to affect recovery and rebuilding are parental effects, Allee effects, sexual selection, and trophic interactions.
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