Sentence examples for model qualification by from inspiring English sources
An important issue in this regard is that model qualification by regulators is not only model validation per se but an evaluation of the modeling and simulation approach as an integral part of drug development.
Model qualification was performed by comparing clinically measured SLD with those predicted by the model, evaluating the uncertainty in parameter values, and using the model to perform a simulation of two sets of 10,000 virtual patients.
For plasma PK profiles and urinary metabolite ratios, model qualification was performed by comparing population mean or individual values of the observations with the model predictions.
CoSMoS, the principled design framework used in the development of ARTIMMUS, for example, shares many key features with the methods for physiological model qualification in drug discovery proposed by Friedrich and Savic.
Details of the flight model qualification test program are presented.
JM created the methotrexate population pharmacokinetic model, provided model qualification and created the forecasting algorithm.
A schematic overview of the model qualification is provided in Figure 5.
The level of model qualification is dependent on the question being addressed.
The objective of model qualification is to examine whether the model is suitable for the proposed applications.
Qualification by the Insurance Marketplace Standards Association demonstrates just this kind of dedication.
