In vivo implantation of the scaffolds in a mice calvaria defect model provided substantial evidences of the suitability of these nanocomposites for bone tissue engineering showing a mature and dense collagenous tissue with small foci of mineralization, vascularized areas and the infiltration of osteoblasts and osteoclasts.
† p <.10 *p <.05 **p <.01 ***p <.001 The results from the second model provide substantial clarification of the role of the criteria for dual use on mortality, especially given the diminished statistical power that accrues from unpacking the generic dual use marker into three specific ones.
Despite the risks of publication bias, our findings in all three general additive models provide substantial quantitative support to suggest swine are hosts in which reassortment frequently occurs [ 28, 38, 39].
According to the experimental results, the proposed model adaptation approach provides substantial effectiveness in reducing the mismatch between trained acoustic models and test environments.
This model provides a substantial improvement in cerebrovascular surgical simulation.
Moreover, therapeutic studies of this mAb in WNV-infection micel mice provided substantial protection when administered after 5 days post-infection.
JEM assisted with model development, provided substantial input into the interpretation of results, assisted in the preparation of the final manuscript, and read and approved the final manuscript.
The reader is left feeling there are too many uncertainties piling up here to allow the model to provide substantial novel insight into the process.
This corresponds to a Bayes Factor >3 as defined by Jeffreys [ 37], which provides substantial support for acceptation of the model.
PD modeling, although more challenging than PK modeling, can provide substantial benefits including providing a basis for evaluating alternative dosing strategies and study design.
