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A recent study using the in vitro ESCs differentiation model provided further evidence that Mesp1 plays a key role in specifying cardiac development.
Additional docking experiments with selective hCYP27B1 or hCYP24A1 inhibitors using both the hCYP27B1 model and a triple mutant hCYP24A1 model provided further support for the importance of H-bonding interactions with the three identified active site amino acids.
Finally, adding plasma CT-proET-1 to plasma NT-proBNP in this model provided further prognostic information.
The E2∼Ub bound model provided further evidence that our Parkin structure represents an autoinhibited conformation.
Finally, integration of these results into a mathematical model provided further substantiation to the novel finding that the ground state of the intracellular signaling machinery constitutes an important determinant of the outcome of receptor-induced cellular responses.
An incorporation of these observations into a mathematical model provided further insights into how changes in the basal activation state of the early intermediates defines sensitivity of the signaling machinery to a given cell surface receptor.
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The good agreement between the experimental data and the simulation with the RNG k ε turbulence model provides further validation for this model in confined, annular flows.
The model provides further insight into the understanding of the generation and propagation of guided wave mode patterns in structure-induced anisotropic plates.
The conceptual model provides further knowledge of key aspects to consider when developing persuasive tools that aims to encourage more sustainable modes of transport.
As the results show, the increase in α level increases values of two objective functions of total cost and total environmental effects; that is, the model provides further support against uncertainties.
► We hypothesize that an energy balance model provides further insights into the energy imbalance.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com