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In addition, the authors did not compare their findings with those from other studies, and the use of probabilistic sensitivity analysis would have captured the issue of uncertainty in the model parameters better.
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The new set of NRTL activity model parameters presented better predictive capabilities for liquid liquid and vapor liquid phase equilibria than current available models.
Also, the performance (both theoretical and empirical) could be improved if model inaccuracies are reduced, i.e., if the model parameters are better estimated at a previous stage.
Future investigations can be carried out to improve and perfect the integrated model, such as the optimization of model parameters to better characterize the reactor/module network in the integrated ERN model.
By its very nature, further efforts in ABM development focus on expanding the range and nature of model parameters to better reflect real-life environments and social processes, and this applies to the range of work described in this paper.
This result is not surprising: the more data used to estimate model parameters, the better the classifier performs.
By adopting such a kinetic representation, identifying the regulatory structure of the system becomes synonymous to determining the set of values θ for the model parameters that better fit the available data.
Additionally, a sensitivity analysis is accomplished by use of sensitivity coefficients in order to estimate which model parameters can be better identified from EIS or from cFRA.
From Table 3, we also notice that using the generalized Baum-Welch followed by the MCE to learn the model parameters is a better strategy.
37 It was shown by simulation that PK-VK models lead to more precise estimates of model parameters and provide better description of the viral kinetics during peg-IFN therapy.
Bayesian analysis of this data set demonstrates that the new model of tumour growth not only gives biological interpretation to model parameters, but also provides better quality of predictions, and is better supported by the experimental evidence.
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