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Global SA (ANOVA) was targeted to assess which processes had an impact on the model outcome in our experimental conditions, by exploring the parameter space over the entire biological range of all parameters.
Using this model, outcome in 22 of 23 cases could be appropriately categorised (Table 3).
The activation of AP-1 as a dynamic balance of TF dimers remains the model outcome in a majority of perturbed parameters.
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In the analog world, we had urban planners limited by access to data and their ability to model outcomes in complex city systems.
Moreover this value makes the model outcomes in terms of steady-state optimal debt compatible with average European data on fiscal policy variables (see Viegas and Ribeiro 2013a).
The proposed strategies, as well as the traditional strategies in the literature, are evaluated with respect to reliability (coverage of observations by the envelope of model outcomes) and sharpness (width of the envelope of model outcomes) in different numerical experiments.
The purpose of this study was to model outcomes in laparoscopic hysterectomy with morcellation compared with abdominal hysterectomy for the presumed fibroid uterus and to examine short- and long-term complications and death.
The optimization of the model based on the published BA profile was performed in a manner similar to the SimPops method outlined in previous publications, wherein a genetic algorithm was used to generate values of variable parameters that lead to model outcomes (in this case, BA profiles) that are within the range of experimental data.
The model outcome expressed in terms of SBS as a function of loading frequency is supported by experimental measurements at both high and low loading frequencies.
The work emphasizes a clear (i.e. transparent) communication of the scenario and model outcome, especially in terms of possible uncertainties and biases.
For this model to be applied in clinical decisions making, further validations are imperative in order to assure that this combination of cytokines would successfully model the outcome in other patients populations.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com