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Clearly, there are many ways to model our paradigm.
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Promising data thus far obtained from mouse models for our paradigm radiotracer [111In-DOTA]MG11 and the NEP inhibitor PA have been directly compared herein with results retrieved after treatment of mice with the ACE inhibitor Lis and the NEP inhibitors TO and Race, all of which have been clinically tested previously.
Indeed, using a combination of mouse models and human iPSC models, such as demonstrated in our paradigm, is required to confidently identify relevant astrocytic targets for inflammatory modulation as a potential treatment strategy for neurodegenerative diseases64, 65.
However, this model cannot be applied to our paradigm, which focuses on memory clinic cohorts suspected of having AD or other differential dementia diagnoses.
In the Discussion, we argue why the RW can be considered an appropriate a priori learning model for our particular paradigm, relative to other models of associative learning.
It's about the ability to choose an alternative mental model or paradigm.
It has served as a unifying model or paradigm for explaining geologic phenomena that were formerly considered in unrelated fashion.
Calculation and evaluation of SALI and SCI values could be incorporated into any model building paradigm.
Instead, they seek a reliable role model or paradigm against which they can compare their actions and practices.
Remember that the model minority paradigm isn't just about Asians being great.
One case or example serves as a model, or paradigm, for interpreting other similar cases (Kuhn, 1970, pp. 23, 187 191).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com