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The metabolome of the nematode Caenorhabditis elegans, like that of other model organisms, remained largely uncharacterized until recent studies demonstrated the importance of small molecule-based signaling cascades for many aspects of nematode biology.
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Position effect mechanisms, first discovered and described in model organisms, remain poorly investigated in human pathology.
Basic science and model organisms remain fundamental to advancing our knowledge". The discoveries of Drs. Hall, Robash, and Young explain how plants, animals, and humans adapt their biological rhythm so that it is synchronized with the Earth's rotation.
However, the genome-wide factors that contribute to subtle individual variations in perception and evaluation of odors in humans or model organisms remain to be elucidated.
Although its effects on the lifespan of many model organisms remain controversial (Kasiotis et al., 2013), anticancer (Bhat and Pezzuto, 2002), anti-inflammatory (Donnelly et al., 2004) and beneficial cardiovascular (Wu and Hsieh, 2011) effects have been reported.
While the molecular mechanisms of DNA-protein specificity at the origin of replication have been determined in many model organisms, these interactions remain unknown in the majority of higher eukaryotes and numerous vertebrate viruses.
Many fundamental systems-level questions about photosynthetic organisms remain unanswered.
NPs may create some acute toxicity, but their overall effects on living organisms remain largely unknown.
For the most part, most tropical organisms remain unstudied and unevaluated.
However, its roles in multi-cellular organisms remain unclear.
However many important taxonomic groups of living organisms remain underrepresented.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com