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The latter has been well established for model organisms, but its availability is limited for mosquitoes.
Genome editing using transcription activator-like effector nuclease (TALEN) has been applied for various model organisms but not yet for agricultural pest insects.
Drastic improvements in DNA sequencing technology could dramatically improve the efficiency of positional cloning in zebrafish and other model organisms, but the best strategy for cloning by sequencing has yet to be established.
These new insights into reading the genome apply not only to the fruit fly Drosophila melanogaster and the roundworm Caenorhabditis elegans, modENCODE's two model organisms, but will apply to human beings and many other organisms as well.
"Some circadian rhythm genes we identified have been studied in model organisms, but much less so in humans," said David Hinds, Ph.D, a Principal Scientist and Statistical Geneticist at 23andMe.
To understand the genetic architecture of floral development, including the origin and subsequent diversification of the flower, data are needed not only for a few model organisms but also for gymnosperms, basal angiosperm lineages and early-diverging eudicots.
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"The goal of this work was to identify something like a model organism, but for microbial communities — something we can bring into the lab and easily replicate and manipulate.
In particular, to take an extreme case, a drug that sterilizes an invertebrate model organism, but thereby significantly increases its longevity, might be erroneously considered beneficial.
Also, several of the newly identified miRNAs have unique seeds in this model organism, but similar seeds are found in miRNAs of other species, including vertebrates (Table S1).
Predicting TF binding in yeast is interesting not only because it is the most often considered model organism, but also because yeast has a well-developed nucleosome model [74] and more abundant ChIP-chip data (see [65], [9]).
Caenorhabditis elegans is a preeminent model organism, but the natural ecology of this nematode has been elusive.
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