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In 'Part B' section, we test all methods on five camera devices with the same model and also test all methods on 17 camera devices with the same model or different models.
The differences between our study and that of Kevil et. al. could be due to the different injury model or different cell type utilized in the individual studies.
The results of the French analysis were in line with those previously obtained with the same model or different approaches [ 7, 12, 37, 39].
However, a different choice of model, or different choice of outcome would modify the saliency even if the chosen model was correct.
That may have two reasons: Either the protein interaction data are biased in a way that is not compatible with the GraphAlignment Bayesian model, or different rates of interaction divergence occur between high-confidence orthologs (the training set) and proteins with low sequence similarity.
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Often, some of the input variables are categorical in nature (e.g., pointer variables to alternative models or different types of material, etc).
For curve fitting this may seem simple, but for more complicated models or different conceptualizations of the space of models, things do not look so easy (cf. Myung et al 2001, Kieseppa 2001).
This may be attributed to the different animal models or different detection systems used.
The contrasting findings between our study and the one by Paris and co-workers could be explained by the use of different tumor models or different GSIs - where one of them does not even inhibit Notch processing (JLK6) [39].
This lack of consensus may reflect different models or different stages of the disease process.
The overall transcript profiles in these microarray experiments are diverse, although it is not clear as to whether this variation is associated with the use of different cell models or different Echinacea preparations.
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