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Related work on algorithms for feature model optimization was previously discussed in (Sanchez et al. 2013).

One is that the DC model optimization was used to improve the accuracy of maximum arrival power at each load point.

Validation/ANN model optimization was performed by applying criteria adapted from those detailed by Mol and colleagues for simultaneous determination of chemical residues in feed and food matrices (Mol et al. [2008]), and Belgrano and colleagues for the application of ANN to primary production time-series data (Belgrano et al. [2001]), respectively.

Model optimization was performed by 5-fold cross-validation.

Model optimization was finalized with a full energy minimization using the GROMACS97 force field [ 124] as implemented in DEEPVIEW.

Model optimization was conducted using Matlab's cost-minimization function ' patternsearch' with a cost function based on the coefficient of determination, R. Experimental and computational integration involved two stages.

(4) The optimal operating conditions of the IFCW obtained through model optimization are as follows: OID is 10.05 d, HRT is 51.45 h, and water depth is 552.64 mm.

Further concept model optimization is needed.

The results of the model optimization are confirmed by AFM.

In this model, optimization is achieved as a function of cost savings vs. customer comfort using mathematical market analysis.

Our model optimization is based on Ref [ 22].